【Scientific Research Achievements】 Discovery of novel covalent selective estrogen receptor degraders against endocrine-resistant breast cancer
2023.05.16【Scientific Research Achievements】 Discovery of a Novel Class of PROTACs as Potent and Selective Estrogen Receptor α Degraders to Overcome Endocrine-Resistant Breast Cancer In Vitro and In Vivo
2023.05.12【Scientific Research Achievements】 Chemoenzymatic synthesis of C14-functionalized steroids
2023.04.19【Scientific Research Achievements】 Cryo-EM structures of human monkeypox viral replication complexes with and without DNA duplex
2023.03.28【Scientific Research Achievements】 Insights into azalomycin F assembly-line contribute to evolution-guided polyketide synthase engineering and identification of intermodular recognition
2023.02.14【Scientific Research Achievements】 Structural basis of regulated m7G tRNA modification by METTL1–WDR4
2023.01.07【Scientific Research Achievements】 In Situ Formation of o-Phenylenediamine Cascade Polymers Mediated by Metal−Organic Framework Nanozymes for Fluorescent and Photothermal Dual-Mode Assay of Acetylcholinesterase Activity
2022.12.19【Scientific Research Achievements】 A swellable bilateral microneedle patch with core-shell structure for rapid lactate analysis and early melanoma diagnosis
2022.12.07【Scientific Research Achievements】 Structures of the R-type human Cav2.3 channel reveal conformational crosstalk of the intracellular segments
2022.12.01【Scientific Research Achievements】 Structural basis for the severe adverse interaction of sofosbuvir and amiodarone on L-type Cav channels
2022.11.23【Scientific Research Achievements】 Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2′-Chloropentostatin Biosynthesis
2022.10.28【Scientific Research Achievements】 Self-Assembled Corrole/Chitosan Photothermal Nanoparticles for Accelerating Infected Diabetic Wound Healing
2022.10.17
